Adenike is an internationally recognized climate change activist. She leads the pan-African organization "I Lead Climate Action Initiative" and is a pioneer of the ecofeminist movement and green democracy in Africa. A local climate leader in her home country of Nigeria, she served as Nigeria's youth delegate to the United Nations Framework Convention on Climate Change at COP25 in Madrid. She went on to represent her country again at COP26 and COP27. Adenike was awarded the Ambassador of Conscience Award by Amnesty International Nigeria in recognition of her fight for both climate justice and human rights. In 2019, she participated in the first United Nations Youth Summit in New York, and in 2021 she developed an online curriculum on "Ecofeminism and Climate Change in Africa". She has recently been invited to be an International Climate Protection Fellow at the Alexander von Humboldt Foundation in Bonn.

At THE NEW INSTITUTE, Adenike was involved in the program Black Feminism and the Polycrisis.